Toxicological risk assessment evaluates the potential impact of a chemical on humans and the environment. It helps establish safe handling practices and meet regulatory standards. Key steps include hazard identification, dose-response assessment, exposure evaluation, and overall risk characterization.

Industries including pharmaceuticals, cosmetics, consumer goods, agriculture, food and supplements, and household products rely on chemical safety assessments to ensure regulatory compliance and safeguard human health and the environment.

REACH (Registration, Evaluation, Authorisation, and Restriction of Chemicals) is the EU regulation ensures chemical safety for human and the environment. Manufacturers, importers, and downstream users must identify risks, submit safety data, register substances with European Chemicals Agency (ECHA), and manage hazards. REACH applies to all chemical substances, including those in everyday products.

Under REACH, all chemical information submitted to ECHA must follow the IUCLID (International Uniform Chemical Information Database) format. An IUCLID dossier is a standardized digital file containing a chemical’s properties, toxicological and ecotoxicological data, and regulatory compliance details. It is essential for REACH registration, chemical safety assessments, and regulatory submissions.

SciQra offers expert chemical safety and toxicological risk assessments using advanced New Approach Methodologies (NAMs), including in vitro assays, in silico tools, read-across strategies, and Benchmark Dose (BMD) modeling. We also prepare comprehensive toxicological profiles for chemicals and their by-products, ensuring scientific rigor, regulatory compliance, and safety across global markets.